Ricerche scientifiche

Raccolta di studi e ricerche scientifiche relative allo yoga e al Parkinson.

The Effects of Mindfulness Meditation-Based Complex Exercise Program on Motor and Nonmotor Symptoms and Quality of Life in Patients with Parkinson's Disease

Hye Gyeong Son,1 Eun-Ok Choi2, *, *

1 Department of Nursing, Kosin University, Busan, Republic of Korea

2 Department of Nursing, College of Medicine, Inje University, Busan, Republic of Korea

Purpose: The present study was to examine the effect of a meditation-based exercise program on the motor and non-motor symptoms of Parkinson's disease (PD).

Methods: Sixty three PD patients who were recruited from a university hospital were randomly assigned to the experimental group (n 1⁄4 33) and to the control group (n 1⁄4 30). Participants completed an 8-week Mindfulness Meditation-based Complex Exercise Program (MMBCEP) that included 6 sessions. Before and after the intervention, the Six-Minute Walk Test (6MWT), elastic band pull, chair stand test, and 2.45-meter walk test were administered for the motor symptoms and the Korean Version of Geriatric Depression Scale, The State-Trait Anxiety Inventory (STAI), the Korean-Montreal Cognitive Assessment, Parkinson's Disease Sleep Scale (PDSS), Activities of Daily Living (ADL), and the Quality of Life of Patients with Parkinson's Disease (PDQL) were administered for non-motor symptoms.

Results: Significant improvements in the motor symptoms (i.e., muscle strength (lower and upper ex- tremity), balance, and muscle endurance) and in the non-motor symptoms (i.e., anxiety, depression, cognitive functions, sleep disturbance, quality of life, and activities of daily living) were observed. Conclusions: MMBCEP, a complex exercise program-based on mindfulness meditation, is associated with increased motor symptoms, decreased emotional disturbances (anxiety and depression) and sleep disturbance, and improved cognitive functions, quality of life, and activities of daily living. Future research should test the effects of MMBCEP with more representative PD patients.

© 2018 Korean Society of Nursing Science, Published by Elsevier Korea LLC. This is an open access article

Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease. A Randomized Clinical Trial.

Jojo Y. Y. Kwok, PhD, MPH, BN, RN; Jackie C. Y. Kwan, MSocSc, PDMH, BSW, RSW; M. Auyeung, MBChB;

Vincent C. T. Mok, MD, MBBS; Claire K. Y. Lau, MSc, BN, APN; K. C. Choi, BSc, PhD; Helen Y. L. Chan, PhD, BSN, RN


Question Isyoga-amindfulness-basedexerciseintervention- a safe and favorable coping strategy compared with conventional stretching and resistance training exercise for management of stress and symptoms in people with mild-to-moderate Parkinson disease?

Findings Inthisrandomizedclinicaltrialthatincluded138 patients with Parkinson disease, the mindfulness yoga program appeared to be a safe and favorable coping strategy for patients with Parkinson disease to address their physical and emotional needs. Compared with conventional stretching and resistance training exercise, mindfulness yoga showed additional benefits on psychological distress, spiritual well-being, and health-related quality of life, with comparable benefits related to motor symptoms and mobility.

Meaning Mindfulnessyogaappearedtobeaneffectiveandsafe treatment option for patients with mild-to-moderate Parkinson disease for stress and symptom management; further investigation is warranted to establish its long-term effect and compliance.

Effects of yoga on oxidative stress, motor function, and non-motor symptoms in Parkinson's disease: a pilot randomized controlled trial

Corjena Cheung,1 Rozina Bhimani,1 Jean F. Wyman,1 Jürgen Konczak,2 Lei Zhang,3 Usha Mishra,4 Marcia Terluk,4Reena V. Kartha,4 and Paul Tuite5


To examine the feasibility, acceptability, and preliminary effects of Hatha yoga on oxidative stress, motor function, and non-motor symptoms among individuals with Parkinson's disease (PD).


The study has a pilot randomized controlled trial design with two arms: an immediate treatment group and a wait-list control group. The yoga-for-PD program was implemented via twice weekly 60-min group-based classes for 12 weeks. Participants were assessed at baseline, 12 weeks, and 6 months post-intervention. Outcome measures included oxidative stress, motor function, physical activity, cognitive function, sleep quality, and quality of life. Data on program acceptability and yoga adherence were collected during the intervention and at 6 months post-intervention.


Participants (n = 20) had a mean age of 63 years (SD 8, range 49-75) and disease duration 4.8 years (SD 2.9, range 1-13). All participants had mild-moderate disease severity; 18 (90%) were on dopaminergic medications. Seventeen participants (85%) attended at least 75% of the classes and 4 (20%) attended all classes. Most participants (n = 17) reported they "definitely enjoyed" the intervention program. No adverse events were reported. At 12 weeks, there were no major differences in blood oxidative stress markers between the two groups. Motor function based on the Unified Parkinson's Disease Rating Scale was better in the treatment group, but their scores on sleep and outlook in Parkinson's Disease Quality of Life (PDQUALIF) Scale and the physical activity levels based on the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire were worse than those of the control group. In within-group comparisons, motor function, cognitive function, and catalase improved but three PDQUALIF domains (social and role function, sleep, and outlook) and physical activity level worsened by the end of the yoga intervention program compared to baseline. The response rate for the 6-month follow-up survey was 74% (n = 14) with six participants (43%) who signed up for a yoga class and four (29%) who practiced it independently. Health problems were the main barrier to yoga practice.


Yoga is feasible and acceptable and may serve as a complementary method for improving motor function in PD. Further research using a larger sample size is needed to determine its impact on oxidative stress and non-motor symptoms.

Trial registration

ClinicalTrials.gov Registration Number: NCT02509610031.

Keywords: Parkinson's disease, Yoga, Oxidative stress, Motor function, Non-motor symptoms